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The PC-PTSD-5 was used as the screening measure, a modified version of the PTSD module of the MINI-International Neuropsychiatric Interview was used to diagnose DSM-5 PTSD, and five brief survey items were used to assess acceptability and preferences. Most of the participants were male, in their 60s, and the majority identified as non-Hispanic White. PARTICIPANTSĪ convenience sample of 398 Veterans participated in the study (response rate = 41 %). Participants also rated screening preferences and acceptability of the PC-PTSD-5. We compared the PC-PTSD-5 results with those from a brief psychiatric interview for PTSD. The objective of this study was to revise the Primary Care PTSD screen (PC-PTSD) to reflect the new Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for PTSD (PC-PTSD-5) and to examine both the diagnostic accuracy and the patient acceptability of the revised measure. Consequently, screening for PTSD has become increasingly common in primary care clinics, especially in Veteran healthcare settings where trauma exposure among patients is common. Posttraumatic Stress Disorder (PTSD) is associated with increased health care utilization, medical morbidity, and tobacco and alcohol use.